Vaccination of what? What specific vaccination? Vaccinations in general? Any one in particular? There are dozens of vaccinations for dozens of infectious organisms.

Be more specific and I will be in return. Luis Pasteur is noted for doing that. But it has been suggested that Nostradamus did some kind of it also. If I can remember the first vaccine was either for small pox or polio? I am leaning more toward polio because the US government was so effective in eradicating it in young children. Lately, however, the US has dropped it from the mandatory vaccines, hence it has recurred in certain areas of the US. http://en.wikipedia.org/wiki/vaccination... The term vaccination is based on the Latin word vaca (cow). It has been coined by doctor Edgard Jenner (1749-1823) who had noticed that in case of cow pox, the girls milking the cows, where never affected by this terrible disease. He decided to "vaccinate" a child with material taken from a cow pox boil. The child did not get ill, and this was the onset of the whole science of vaccination: inoculate the disease to the patient in a very light form , enough to trigger the production of antibodies and prevent the onset from the disease. Evolution of Vaccines

Over 200 years ago, English physician Edward Jenner observed that milkmaids stricken with a viral disease called cowpox were rarely victims of a similar disease, smallpox. This observation led to the development of the first vaccine. In an experiment that was to prove a revelation, Jenner took a few drops of fluid from a pustule of a woman who had cowpox and injected the fluid into a healthy young boy who had never had cowpox or smallpox. Six weeks later, Jenner injected the boy with fluid from a smallpox pustule, but the boy remained free of the dreaded smallpox.